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Examining the Antibiotic Pipeline

In: Policy Responses to the Growing Threat of Antibiotic Resistance

Published: May 2008

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Examining the Antibiotic Pipeline By: Colson A Published In: Policy Responses to the Growing Threat of Antibiotic Resistance	Quantity

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The discovery of unique antibiotic classes has slowed, yet the need for antibiotics for infections caused by resistant bacteria is urgent. Since 1970, only five new classes of antibiotics have been introduced for human use, two of which are limited to topical use. Furthermore, the number of new antibiotics—not just new formulations of existing ones—to be approved by the Food and Drug Administration (FDA) has fallen steadily since 1980.

New antibiotics are on the horizon, but the slow pace and narrow scope of research and development is worrying physicians and public health specialists. In this issue brief, Extending the Cure looks at recently approved and late-stage development antibiotics to determine gaps in supply warranting enhanced research and development.

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