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Two trustees of hospitals that have experience with Transforming Care at the Bedside (TCAB), a nurse-led, quality improvement initiative, cite efficiency, lower staff turnover, and staff and patient satisfaction as reasons why TCAB makes sense from a hospital’s business point of view. In this interview appearing in a special supplement to the American Journal of Nursing, Mark Laskow, a trustee at the University of Pittsburgh Medical Center, and Leslie Newman, a trustee at Children’s Memorial Hospital in Chicago, reflect on their institutions’ implementation of TCAB.