Characterization of Left Ventricular Diastolic Function in Hypertension by Use of Doppler Tissue Imaging and Color M-Mode Techniques

The current study examined how pulsed wave Doppler (PWD), Doppler tissue imaging (DTI) and color M-mode (CMM) indices were used clinically to ascertain left ventricular (LV) diastolic dysfunction for individuals with hypertension (HTN). Participants were 278 patients placed in one of the following groups: healthy controls, HTN without LV hypertrophy (LVH), or HTN with LVH. PWD, DTI, and CMM were used to measure diastolic functioning for all participants with comparisons than made between groups.

Key Findings:

  • Statistically significant differences between groups on LV relaxation and filling pressures were found only when DTI methods were used.
  • CMM-indices did not identify significant differences between groups of patients.
  • Increased LV filling pressures might be an indicator of dysfunction leading to hypertensive heart disease.
  • DTI methods were effective in evaluating LV relaxation and filling pressure as related to HTN.