Accelerating the discovery and validation of therapeutic drug targets: 2005

The purpose of this project is to test and disseminate a new way to organize medical research and the application of that research knowledge to a particular problem. The Myelin Repair Foundation (MRF) is pioneering a new outcome-directed research model that is a unique combination of disease-focused scientific collaboration and best business practices. The MRF mission is to discover how myelin, the protective sheath around neurons, is created, damaged, and can be repaired, with the ultimate goal of designing new treatments for multiple sclerosis. The research model has relevance for many diseases and for how the National Institutes of Health (NIH) funds basic research. Foundation support will enable MRF to develop the infrastructure necessary to achieve sustainability and then to document and disseminate the model to other disease groups and the broader research field. The project will be considered successful if it: (1) enables MRF to achieve self-sustainability by 2009; (2) influences the funding of other disease-based research organizations; and (3) is recognized by NIH either through funding or adoption of one or more components of the model.

Grant Details

Amount Awarded $1,217,600.00

Awarded on: 7/28/2005

Time frame: 8/1/2005 - 7/31/2008

Grant Number: 52461


Myelin Repair Foundation Inc.

18809 Cox Avenue, Suite 190
Saratoga, 95070-6618


Scott F. Johnson
Project Director