Harold Amos Medical Faculty Development Program - Carmen E. Guerra, M.D.

The Foundation's Harold Amos Medical Faculty Development Program was designed to provide four-year postdoctoral research awards offered to historically disadvantaged physicians who are committed to developing careers in academic medicine, to improving the health of underserved populations, and to furthering the understanding and elimination of health disparities.This grant supports a study to investigate whether curcumin modulates immunohistochemical, cellular biomarkers of elevated colorectal cancer risk in patients with previously resected, sporadic colorectal adenomas. In addition, the study will explore, ex vivo, whether adenomatous polyps or the normal appearing colonic mucosa of patients with adenomatous polyps contains COX-2 mediated mutagenic DNA adducts and explore changes in the concentrations of these adducts in response to curcumin.

Grant Details

Amount Awarded $365,400.00

Awarded on: 6/14/2005

Time frame: 7/1/2005 - 6/30/2009

Grant Number: 51895


University of Pennsylvania Perelman School of Medicine

295 John Morgan Building
3620 Hamilton Walk
Philadelphia, 19104-0001


Carmen Estela Guerra
Project Director