Research on nicotine exposure and dependence associated with different levels of adolescent smoking

The ability to study how adolescents smoke is critical to understanding how the process of addiction occurs, and was discussed as a major research deficit at the Foundation's tobacco conference in Sundance, Utah. Contemporary data from British and U.S. studies suggest that about one-third to one-half of those who try smoking cigarettes escalate to regular patterns of use and to nicotine dependence. This program contract provides support for a collaborative research project between the Centre for Addiction and Mental Health, Addiction Research Foundation Division, and Virginia Commonwealth University to measure nicotine exposure and nicotine dependence associated with different levels of cigarette use by adolescents. The project will help clarify the development of tobacco use and nicotine dependence in adolescents. Researchers will study a sample of adolescent smokers representing a cross-section of early smoking behavior, from the stage at which the adolescent is beginning to experiment with cigarettes, through episodic use, to regular use. The subject's extent and patterns of smoking will be determined by questionnaire, and subjective and biological measurements will be obtained before and after smoking. In this way, researchers will be able to correlate questionnaire responses, subjective scores, and biological and topographic measures of tobacco exposure.

Grant Details

Amount Awarded $50,000.00

Awarded on: 9/4/1998

Time frame: 10/1/1998 - 9/30/2001

Grant Number: 35116


Centre for Addiction and Mental Health, Addiction Research Foundation Division

33 Russell Street
Toronto, M5S 2S1


William A. Corrigall
Project Director