Category Archives: Clinical research
SreyRam Kuy, MD, MHS, is an alumna of the Robert Wood Johnson Foundation (RWJF) Clinical Scholars program, and a vascular surgery fellow at the Medical College of Wisconsin.
Gallbladder disease, and specifically gallstones, can present as pain in the upper abdomen, usually after eating fatty foods. More severely, gallstones can progress to an inflammation and infection called cholecystitis or cholangitis, both of which require prompt surgical treatment. Gallbladder disease is an important medical problem as it accounts for $650 billion in health care costs annually in the United States[i], making it the second most costly digestive disease in the country.[ii] With more than 700,000 cholecystectomies (surgeries to remove the gallbladder) performed annually in the United States, gallbladder disease is the number one reason for abdominal surgery in the nation.[i] Cholecystectomies can be done with traditional surgery (open cholecystectomy) or performed minimally invasively (laparoscopic cholecystectomy).
The National Health and Nutrition Examination Survey estimates 6.3 million men and 14.2 million women in the United States have gallbladder disease.[iii] It occurs two times more frequently in women than in men.[i][iv] However, during the reproductive years, women have a four-fold higher prevalence of gallstones than men.[iii] As a result of its disproportionate burden on women, gallbladder disease is a critically important topic in women’s health.
There is currently a lack of consensus on whether a patient’s gender affects how soon they get surgery for cholecystitis, what type of surgery they get (open versus laparoscopic cholecystectomy), and how they do after surgery. My prior work and that of my colleagues has clearly shown that older age negatively impacts how patients do following cholecystectomy.[v] Therefore, to determine whether gender, independent of other factors, affects outcome, we examined a national group of patients hospitalized with cholecystitis over an eight-year period, age-matched to account for the effect of age, and identified gender-based differences in patients hospitalized with cholecystitis. We measured outcomes of women compared with men who underwent cholecystectomy during that admission for cholecystitis, and identified factors associated with outcome.
Human Capital News Roundup: Television ads for statins, advanced nursing education, treatment for gunshot wounds, and more.
Around the country, print, broadcast and online media outlets are covering the groundbreaking work of Robert Wood Johnson Foundation (RWJF) leaders, scholars, fellows and grantees. Some recent examples:
In a piece about the growing need for advanced nursing education, Nurse.com interviewed a group of nurse leaders working to fulfill a recommendation from the Institute of Medicine report, The Future of Nursing: Leading Change, Advancing Health, which calls for doubling the number of doctorate-level nurses by 2020. Among those quoted: Christine Kovner, RN, PhD, FAAN, co-principal of RWJF’s RN Work Project; RWJF Executive Nurse Fellows alumna Jane Kirschling, RN, DNS, FAAN; and Susan Bakewell-Sachs, RN, PhD, PNP-BC, program director for the New Jersey Nursing Initiative, a program of RWJF and the New Jersey Chamber of Commerce Foundation.
Nurse.com and Infection Control Today report on an RWJF-supported study that finds hospitals that have higher percentages of nurses with baccalaureate degrees have lower rates of postsurgical mortality. The study, published in the March issue of Health Affairs, stems from the Future of Nursing: Campaign for Action. Read more about the study.
“I recently traveled to Singapore, where I met with other doctors and told about being the emergency department (ED) doctor at the University of Colorado Hospital the morning of the Aurora theater shootings on July 20, 2012,” RWJF Clinical Scholars alumna Comilla Sasson, MD, MS, FACEP, writes in an op-ed for the Denver Post. “One thing dawned on me as I spoke: I had seen more gunshot wound victims in that one night than these doctors will see in their entire careers.” Read a post Sasson wrote for the RWJF Human Capital Blog about the Aurora theater shootings, and learn more about her experience talking to the national news media afterward.
Project L/EARN is an intensive, 10-week summer internship for undergraduate college students who are from socioeconomic, ethnic, and cultural groups that have been traditionally underrepresented in graduate education. The program, funded in part by the Robert Wood Johnson Foundation, provides students with training, experience and mentoring to make them stronger candidates for admission to graduate programs. Interns attend lecture sessions, complete Graduate Record Examinations (GRE) preparation, and work with mentors to write a research paper, which they present as a poster. This year’s program was held at the Institute for Health, Health Care Policy and Aging Research at Rutgers University. This is part of a series of posts where scholars who completed the program discuss the experience. Learn more about Project L/EARN.
Hometown: Jersey City, NJ
Rising junior at Rutgers University
Internship Research Project: Breast Cancer Survivors’ Perceptions of Quality Cancer-Related Care from Primary Care Providers
Human Capital Blog: What aspect of the Project L/EARN internship has been most helpful and why?
Stephanie Jimenez: The most helpful part of my Project L/EARN experience this summer was the guidance that I received from my mentor as well as the things I learned from my instructional staff. The feedback I gained from my presentation helped me gain perspective.
RWJF Scholars in Health Policy Research National Program Director Alan B. Cohen, Sc.D., had a letter in the December 29, 2010 New York Times (Avastin: Judging the Risks vs. Benefits), noting that Food & Drug Administration (FDA) approval of new drugs “commonly opens the floodgates to widespread use, often by many patients for whom the benefits are questionable.” Cohen argues that the FDA and the manufacturers of new drugs “should be required to consider the varying effects of a new drug on different groups of people so that drug approval decisions can be targeted at those who will really benefit while preventing or minimizing adverse effects for those who won’t.”
Bruce Barrett, M.D., Ph.D., Associate Professor at the University of Wisconsin School of Medicine and Public Health and an alum of RWJF Generalist Physician Faculty Scholar program (2003), is getting some noteworthy press attention for his recent study on the effect of Echinacea on the common cold. (Short version: He finds it doesn’t make much difference.) Among the media outlets that have reported on the study so far are NPR and CNN. An up-to-the-minute list of media hits, via Google news search, is here.